Magical Maladies & Mishaps
These are a few possible problems and conditions that can occur when the powers of magic are mishandled, or when magic is released without proper control. This is of course not an exhaustive list, and when magic effects interact, they can have sometimes (indeed, often) have effects that are undesirable.
Spell Miscellanea
Even permanent magical items can begin to become unstable with centuries of neglect. Some scholars contend that arcane items can become cursed when abandoned for centuries, while others believe these items simply fade from their former potency.
Magic Items & Places
Maladies
Not all diseases have natural causes, and even some "natural" ills have effects on those who cast spells. Some of the maladies listed below can effect priests and mages in various ways.
Regions
Not all casters are equal, nor are the places where magic might be cast.Weather
Warlocks
Warlocks are a special case, as their connection to magic (and the World) is so entirely different than that of other spellcasters. Even when a warlock and a wizard (or bard or cleric of sorcerer) cast the same spell, the effects can sometimes vary in subtle ways that are hard to describe. These differences vary depending upon the warlock's patron (and often their pact), and sometimes go unnoticed. While differences exist between other classes (even when casting what is nominally the same spell), warlocks tend to be more extreme.
Soul Fragments
When a character dies, roll a d20, and on a roll of (1 + character level / 4) or below, that character's soul momentarily produces (1d6-1 + character level/5) shards. These shards or fragments can affix to important items carried or worn by the character. The DM determines which items these fragments may attach to, starting with the item most important to the character. Roll another d20, and make a Wisdom saving throw with a DC determined from the table below:Items that have gained a soul fragment become the stuff of legend, often having stories and lore surrounding it generations and centuries hence. Some items may even become more significant (in history) than it's owners.

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